Saadati et al 2022. My Score – Poor, 2 of 5. The study didn’t really show much.

Effects of a gluten challenge in patients with irritable bowel syndrome: a randomized single-blind controlled clinical trial

New Study: My Interpretation – For those with IBS symptoms, A low Gluten Diet can improve symptoms. Also supports the existence of NCGS. 11 of 50 patients = 22% of IBS patients.

Piper et al. 2004. Effect of Prolyl Endopeptidase on Digestive-Resistant Gliadin Peptides in Vivo

Notably, the BBM action on P5, the 33-mer known to be highly immunogenic by its capacity to stimulate T cell replication, is minimal (Fig. 1). When PEP concentration was increased to 190U/l, in the in vivo perfusion experiments, P5 (33-mer) could be shown to be completely cleaved to small nontoxic peptides (Fig. 3).

Gregorio M et al. 2018. Identification and characterization of proteolytically resistant gluten-derived peptides†

Study saying that Glutenin gets degraded in gastrointestinal tract. Also lists lots of epitopes.